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Assay Detail

CHEMBL4340472

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity in human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTS assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Target

HCT-116 (CHEMBL394)
Type CELL-LINE
Organism Homo sapiens

Publication

Lamellarin Sulfates from the Pacific Tunicate <i>Didemnum ternerratum</i>.
Bracegirdle J, Robertson LP, Hume PA, Page MJ, Sharrock AV, Ackerley DF, Carroll AR, Keyzers RA.
J Nat Prod (2019) 82 : 2000 -2008
PubMed 31306000 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.19 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4437011 1 5.37
CHEMBL4467426 1 5.01
CHEMBL4471385 1 -
CHEMBL4453607 1 -
CHEMBL4538046 1 -
CHEMBL4456710 1 -
CHEMBL4470639 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4437011 IC50 = 4300.0 nM 5.37
CHEMBL4467426 IC50 = 9700.0 nM 5.01
CHEMBL4471385 IC50 - -
CHEMBL4453607 IC50 - -
CHEMBL4538046 IC50 - -
CHEMBL4456710 IC50 - -
CHEMBL4470639 IC50 - -