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Assay Detail

CHEMBL4343389

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Functional
Antiproliferative activity against human CCRF-CEM cells assessed as reduction in cell viability after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CCRF-CEM
Confidence 1 — Organism
Curated By Autocuration

Target

CCRF-CEM (CHEMBL382)
Type CELL-LINE
Organism Homo sapiens

Publication

1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
Xu Z, Zhao SJ, Liu Y.
Eur J Med Chem (2019) 183 : 111700 -111700
PubMed 31546197 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.31 6.31

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4568280 1 6.31
CHEMBL4548174 1 6.31

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4568280 IC50 = 490.0 nM 6.31
CHEMBL4548174 IC50 = 490.0 nM 6.31