Assay Detail
Binding
CHEMBL4344005
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mouse STING by ITC assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Stimulator of interferon genes protein (CHEMBL4523311) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Targeting Stimulator of Interferon Genes (STING): A Medicinal Chemistry Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.19 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL71263 | VADIMEZAN | 3.0 | 1 | 6.89 |
| CHEMBL1569545 | CRIDANIMOD | 3.0 | 1 | 5.48 |
| CHEMBL323197 | MANGOSTIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL71263 | VADIMEZAN | Kd | = | 130.0 | nM | 6.89 |
| CHEMBL1569545 | CRIDANIMOD | Kd | = | 3300.0 | nM | 5.48 |
| CHEMBL323197 | MANGOSTIN | Kd | = | 137000.0 | nM | - |