Assay Detail
Binding
CHEMBL4344281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of rat hepatocytes AMPK alpha1/beta2/gamma1 expressed in baculovirus infected Sf9 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | Sf9 |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.76 | 8.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4167177 | — | — | 1 | 8.12 |
| CHEMBL4082745 | — | — | 1 | 7.40 |
| CHEMBL3891221 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4167177 | — | EC50 | = | 7.5 | nM | 8.12 |
| CHEMBL4082745 | — | EC50 | = | 40.0 | nM | 7.40 |
| CHEMBL3891221 | — | EC50 | > | 40000.0 | nM | - |