Assay Detail
Binding
CHEMBL4348590
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Pseudomonas aeruginosa PqsD
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
2-heptyl-4(1H)-quinolone synthase PqsD (CHEMBL3559673) ↗| Type | SINGLE PROTEIN |
| Organism | Pseudomonas aeruginosa |
Publication
Anti-PqsR compounds as next-generation antibacterial agents against Pseudomonas aeruginosa: A review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.23 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4453677 | — | — | 1 | 5.77 |
| CHEMBL4587386 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4453677 | — | IC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL4587386 | — | IC50 | = | 21000.0 | nM | 4.68 |