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Assay Detail

CHEMBL4349541

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Binding
Inhibition of MPS1 (unknown origin) in presence of 10 uM ATP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Dual specificity protein kinase TTK (CHEMBL3983)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular design and anticancer activities of small-molecule monopolar spindle 1 inhibitors: A Medicinal chemistry perspective.
Wang S, Zhang M, Liang D, Sun W, Zhang C, Jiang M, Liu J, Li J, Li C, Yang X, Zhou X.
Eur J Med Chem (2019) 175 : 247 -268
PubMed 31121430 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.95 7.95

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3809829 1 7.95

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3809829 IC50 = 11.2 nM 7.95