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Assay Detail

CHEMBL4349552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of glioblastoma patient derived MPS1
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Dual specificity protein kinase TTK (CHEMBL3983)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Molecular design and anticancer activities of small-molecule monopolar spindle 1 inhibitors: A Medicinal chemistry perspective.
Wang S, Zhang M, Liang D, Sun W, Zhang C, Jiang M, Liu J, Li J, Li C, Yang X, Zhou X.
Eur J Med Chem (2019) 175 : 247 -268
PubMed 31121430 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4474534 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4474534 IC50 = 50.0 nM 7.30