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Assay Detail

CHEMBL4353104

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Irreversible inhibition of AChE (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Multi-target design strategies for the improved treatment of Alzheimer's disease.
Zhang P, Xu S, Zhu Z, Xu J.
Eur J Med Chem (2019) 176 : 228 -247
PubMed 31103902 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.75 5.75

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3291021 1 5.75

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3291021 IC50 = 1800.0 nM 5.75