Assay Detail
Functional
CHEMBL4353417
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against mouse NIH/3T3 cells assessed as decrease in cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Triptolide: Medicinal chemistry, chemical biology and clinical progress.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.57 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4566346 | — | — | 1 | 8.00 |
| CHEMBL4442774 | — | — | 1 | 7.40 |
| CHEMBL463763 | TRIPTOLIDE | 3.0 | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4566346 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4442774 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL463763 | TRIPTOLIDE | IC50 | = | 50.0 | nM | 7.30 |