Assay Detail
Binding
CHEMBL4354904
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Binding affinity to Streptococcus mutans Sortase A
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Streptococcus mutans |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Targeting <i>S. mutans</i> biofilms: a perspective on preventing dental caries.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.95 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL7976 | CHALCONE | — | 1 | 5.30 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.99 |
| CHEMBL28626 | MORIN | — | 1 | 4.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL7976 | CHALCONE | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL140 | CURCUMIN | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL28626 | MORIN | IC50 | = | 27200.0 | nM | 4.57 |