Assay Detail
Binding
CHEMBL4355144
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human PTP1B (1 to 322 residues) expressed in Escherichia coli assessed as reduction in p-nitrophenol formation using p-nitrophenyl phosphate as substrate incubated for 30 mins by spectrophotometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 1 (CHEMBL335) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Potential Anticancer Agents Characterized from Selected Tropical Plants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.18 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1782238 | COCHINCHINOXANTHONE | — | 1 | 5.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1782238 | COCHINCHINOXANTHONE | IC50 | = | 6600.0 | nM | 5.18 |