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Assay Detail

CHEMBL4355611

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of West Nile virus protease
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism West Nile virus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Genome polyprotein (CHEMBL5419)
Type SINGLE PROTEIN
Organism West Nile virus

Publication

Peptide derivatives as inhibitors of NS2B-NS3 protease from Dengue, West Nile, and Zika flaviviruses.
da Silva-Júnior EF, de Araújo-Júnior JX.
Bioorg Med Chem (2019) 27 : 3963 -3978
PubMed 31351847 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.25 7.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL506092 1 7.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL506092 IC50 = 56.0 nM 7.25