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Assay Detail

CHEMBL4355847

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A375 cells assessed as reduction in cell viability after 72 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A-375
Confidence 1 — Organism
Curated By Autocuration

Target

A-375 (CHEMBL613859)
Type CELL-LINE
Organism Homo sapiens

Publication

Natural Product Albiziabioside A Conjugated with Pyruvate Dehydrogenase Kinase Inhibitor Dichloroacetate To Induce Apoptosis-Ferroptosis-M2-TAMs Polarization for Combined Cancer Therapy.
Wei G, Sun J, Luan W, Hou Z, Wang S, Cui S, Cheng M, Liu Y.
J Med Chem (2019) 62 : 8760 -8772
PubMed 31509699 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.26 5.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1765593 1 5.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1765593 IC50 = 5470.0 nM 5.26