A-375 · CELL-LINE · Homo sapiens
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A-375
Review this target as A-375.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats A-375 as ChEMBL target CHEMBL613859. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | A-375 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as A-375.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1159504 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL4293472 | 10.8 | IC50 | 0.016 | Preclinical |
| CHEMBL3752213 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL378080 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL292702 | 10.43 | IC50 | 0.037 | Clinical |
| CHEMBL94657 | 10.3 | IC50 | 0.04997 | Clinical |
| CHEMBL96926 | 10.05 | IC50 | 0.08921 | Preclinical |
| CHEMBL3747047 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL1078226 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL3356795 | 9.52 | IC50 | 0.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2,004 | 3,558 | 5.8 |
| organism-based format | 273 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 35 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 17 | 11 | 5.4 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |