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Assay Detail

CHEMBL4356029

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Zika virus PLCal_ZV infected in African green monkey Vero cells assessed as reduction in viral titer after 1 hr by plaque assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Zika virus
Cell Type Vero
Confidence 1 — Organism
Curated By Autocuration

Target

Zika virus (CHEMBL4296612)
Type ORGANISM
Organism Zika virus

Publication

Drugs for the Treatment of Zika Virus Infection.
Bernatchez JA, Tran LT, Li J, Luan Y, Siqueira-Neto JL, Li R.
J Med Chem (2020) 63 : 470 -489
PubMed 31549836 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.55 5.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL682 AMODIAQUINE 4.0 1 5.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL682 AMODIAQUINE EC50 = 2800.0 nM 5.55