Assay Detail
Binding
CHEMBL4356095
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of BTK (unknown origin) after 60 mins by FRET assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Exploration of Chirality for Improved Druggability within the Human Kinome.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.85 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3647964 | — | — | 1 | 8.85 |
| CHEMBL1873475 | IBRUTINIB | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3647964 | — | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL1873475 | IBRUTINIB | IC50 | < | 0.5 | nM | - |