Assay Detail
Binding
CHEMBL4356370
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of immunoproteasome subunit LMP7 in human DOX40 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Immunoproteasome: An Emerging Target in Cancer and Autoimmune and Neurological Disorders.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.52 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3319482 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3319482 | — | IC50 | = | 3000.0 | nM | 5.52 |