Assay Detail
Binding
CHEMBL4358956
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]2-BFI from I2IR in Sprague-Dawley rat brain cortex incubated for 45 mins by liquid scintillation spectrometry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Bicyclic α-Iminophosphonates as High Affinity Imidazoline I2 Receptor Ligands for Alzheimer's Disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.05 | 7.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL10316 | IDAZOXAN | 3.0 | 1 | 7.17 |
| CHEMBL4450506 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL10316 | IDAZOXAN | Ki | = | 67.61 | nM | 7.17 |
| CHEMBL4450506 | — | Ki | = | 120.23 | nM | 6.92 |