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Assay Detail

CHEMBL4360802

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Functional
Antiviral activity against Human rhinovirus B3
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human rhinovirus B3
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses.
Egorova A, Ekins S, Schmidtke M, Makarov V.
Eur J Med Chem (2019) 178 : 606 -622
PubMed 31226653 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 8 6.59 6.92

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL96339 1 6.92
CHEMBL96661 1 6.92
CHEMBL330131 1 6.92
CHEMBL96922 1 6.92
CHEMBL330156 1 6.46
CHEMBL96886 1 6.36
CHEMBL95079 1 6.12
CHEMBL95040 1 6.11

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL96339 IC50 = 120.0 nM 6.92
CHEMBL96661 IC50 = 120.0 nM 6.92
CHEMBL330131 IC50 = 120.0 nM 6.92
CHEMBL96922 IC50 = 120.0 nM 6.92
CHEMBL330156 IC50 = 350.0 nM 6.46
CHEMBL96886 IC50 = 440.0 nM 6.36
CHEMBL95079 IC50 = 760.0 nM 6.12
CHEMBL95040 IC50 = 770.0 nM 6.11