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Assay Detail

CHEMBL4360811

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Functional
Antiviral activity against Enterovirus A71 genotype B
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Enterovirus A71
Confidence 1 — Organism
Curated By Autocuration

Target

Enterovirus A71 (CHEMBL612436)
Type ORGANISM
Organism Enterovirus A71

Publication

Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses.
Egorova A, Ekins S, Schmidtke M, Makarov V.
Eur J Med Chem (2019) 178 : 606 -622
PubMed 31226653 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL46646 1 6.52
CHEMBL46381 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL46646 IC50 = 300.0 nM 6.52
CHEMBL46381 IC50 = 300.0 nM 6.52