Assay Detail
ADMET
CHEMBL4361705
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Cytotoxicity against CHO cells measured after 48 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioisosteric ferrocenyl aminoquinoline-benzimidazole hybrids: Antimicrobial evaluation and mechanistic insights.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.15 | 7.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50588 | EMETINE | 4.0 | 1 | 7.79 |
| CHEMBL4536176 | — | — | 1 | 4.79 |
| CHEMBL4458564 | — | — | 1 | 4.41 |
| CHEMBL4457955 | — | — | 1 | 4.39 |
| CHEMBL4548998 | — | — | 1 | 4.38 |
| CHEMBL4444771 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50588 | EMETINE | IC50 | = | 16.2 | nM | 7.79 |
| CHEMBL4536176 | — | IC50 | = | 16160.0 | nM | 4.79 |
| CHEMBL4458564 | — | IC50 | = | 38870.0 | nM | 4.41 |
| CHEMBL4457955 | — | IC50 | = | 40930.0 | nM | 4.39 |
| CHEMBL4548998 | — | IC50 | = | 42010.0 | nM | 4.38 |
| CHEMBL4444771 | — | IC50 | > | 50000.0 | nM | - |