Assay Detail
Binding
CHEMBL4362038
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant His-tagged human EGFR (645 to 1186 residues) cytoplasmic domain expressed in baculovirus infected Sf9 cells incubated for 10 mins by time resolved fluorimetry
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Sf9 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Cinnamamide: An insight into the pharmacological advances and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.21 | 5.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2336355 | N-(2-METHOXYPHENYL)CINNAMAMIDE | — | 1 | 5.29 |
| CHEMBL1998736 | N-(2-FLUOROPHENYL)CINNAMAMIDE | — | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2336355 | N-(2-METHOXYPHENYL)CINNAMAMIDE | IC50 | = | 5160.0 | nM | 5.29 |
| CHEMBL1998736 | N-(2-FLUOROPHENYL)CINNAMAMIDE | IC50 | = | 7370.0 | nM | 5.13 |