Assay Detail
Functional
CHEMBL4364948
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Enterovirus A71 695F infected in human muscular rhabdomyosarcoma cells assessed as reduction in virus-induced cell death incubated for 3 days by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus A71 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Application of Dually Activated Michael Acceptor to the Rational Design of Reversible Covalent Inhibitor for Enterovirus 71 3C Protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.85 | 7.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL20210 | RUPINTRIVIR | 2.0 | 1 | 7.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL20210 | RUPINTRIVIR | EC50 | = | 14.0 | nM | 7.85 |