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Assay Detail

CHEMBL4367633

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Selective estrogen receptor down regulator activity at ERalpha (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Estrogen receptor (CHEMBL206)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Boron in drug design: Recent advances in the development of new therapeutic agents.
Fernandes GFS, Denny WA, Dos Santos JL.
Eur J Med Chem (2019) 179 : 791 -804
PubMed 31288128 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.39 8.39

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4526356 ZB-716 1.0 1 8.39

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4526356 ZB-716 IC50 = 4.1 nM 8.39