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Assay Detail

CHEMBL4368771

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Binding
Binding affinity to 5'-fluorescein-tagged bacterial ribosomal A site 27-nucleotide hairpin RNA construct by fluorescence analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bacteria
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Use of a fluorescence assay to determine relative affinities of semisynthetic aminoglycosides to small RNAs representing bacterial and mitochondrial A sites.
Waduge P, Sati GC, Crich D, Chow CS.
Bioorg Med Chem (2019) 27 : 115121 -115121
PubMed 31610941 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 8.30 8.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL184618 FRAMYCETIN 3.0 1 8.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL184618 FRAMYCETIN Kd = 5.0 nM 8.30