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Assay Detail

CHEMBL4368976

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to BRD4 (unknown origin) by surface plasmon resonance analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Bromodomain-containing protein 4 (CHEMBL1163125)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Targeting Brd4 for cancer therapy: inhibitors and degraders.
Duan Y, Guan Y, Qin W, Zhai X, Yu B, Liu H.
Medchemcomm (2018) 9 : 1779 -1802
PubMed 30542529 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.64 7.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2177300 1 7.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2177300 Kd = 23.0 nM 7.64