Assay Detail
Binding
CHEMBL4369204
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine spleen PNP using inosine as substrate by xanthine oxidase coupled assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The transition to magic bullets - transition state analogue drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.91 | 10.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218291 | FORODESINE | 4.0 | 1 | 10.64 |
| CHEMBL473922 | — | — | 1 | 10.52 |
| CHEMBL1236524 | GALIDESIVIR | 2.0 | 1 | 5.58 |
| CHEMBL4574213 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218291 | FORODESINE | Ki | = | 0.023 | nM | 10.64 |
| CHEMBL473922 | — | Ki | = | 0.03 | nM | 10.52 |
| CHEMBL1236524 | GALIDESIVIR | Ki | = | 2600.0 | nM | 5.58 |
| CHEMBL4574213 | — | Ki | = | 422000.0 | nM | - |