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Assay Detail

CHEMBL4369688

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Functional
Agonist activity at human mGlu7 expressed in CHO cells assessed as reduction in forskolin-induced cAMP production
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type CHO
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Metabotropic glutamate receptor 7 (CHEMBL3777)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present.
Vázquez-Villa H, Trabanco AA.
Medchemcomm (2019) 10 : 193 -199
PubMed 30881607 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.00 9.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4456545 1 9.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4456545 EC50 = 1.0 nM 9.00