Metabotropic glutamate receptor 7 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q14831. Use UniProt Q14831 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q14831 as the stable identity anchor, then attach disease evidence before program review.
Metabotropic glutamate receptor 7
Review this target as Metabotropic glutamate receptor 7, mapped to UniProt Q14831. Sequence length is 915 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Metabotropic glutamate receptor 7 as ChEMBL target CHEMBL3777, mapped to UniProt Q14831. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Metabotropic glutamate receptor 7 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q14831 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Metabotropic glutamate receptor 7 |
| UniProt Accession | Q14831 |
| Component Type | Protein |
| Sequence Length | 915 aa |
Metabotropic glutamate receptor 7
Review this target as Metabotropic glutamate receptor 7, mapped to UniProt Q14831. Sequence length is 915 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4456545 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL4446583 | 8.92 | EC50 | 1.205 | Preclinical |
| CHEMBL5285249 | 8.22 | EC50 | 6.0 | Preclinical |
| CHEMBL4556629 | 8.16 | EC50 | 6.9 | Preclinical |
| CHEMBL5266235 | 8.15 | EC50 | 7.0 | Preclinical |
| CHEMBL5280256 | 7.55 | EC50 | 28.0 | Preclinical |
| CHEMBL4443735 | 7.54 | EC50 | 29.2 | Preclinical |
| CHEMBL5288955 | 7.42 | EC50 | 38.0 | Preclinical |
| CHEMBL5286456 | 7.26 | EC50 | 55.0 | Preclinical |
| CHEMBL4174742 | 7.2 | IC50 | 63.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 33 | 43 | 5.8 |
| cell-based format | 15 | 11 | 7.2 |
| assay format | 7 | 16 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 38 | 30 | 5.2 |
| assay format | 13 | 25 | 5.8 |
| single protein format | 2 | 1 | 7.2 |