Assay Detail
Functional
CHEMBL4372158
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Antiviral activity against Human poliovirus 2 10232 infected in human HeLa cells assessed as reduction in virus-induced cytopathic effect after 72 hrs by crystal violet staining-based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Poliovirus 2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In Vitro Antiviral Activity of New Oxazoline Derivatives as Potent Poliovirus Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.37 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4542831 | — | — | 1 | 7.64 |
| CHEMBL166427 | — | — | 1 | 6.27 |
| CHEMBL4440889 | — | — | 1 | 5.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4542831 | — | EC50 | = | 23.0 | nM | 7.64 |
| CHEMBL166427 | — | EC50 | = | 540.0 | nM | 6.27 |
| CHEMBL4440889 | — | EC50 | = | 6330.0 | nM | 5.20 |