Assay Detail
Binding
CHEMBL4372185
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Inhibition of human cathepsin G using Suc-AAPF-MCA as substrate after 30 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Highly Potent and Selective Plasmin Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold Attenuate Fibrinolysis in Plasma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.85 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4588827 | — | — | 1 | 5.11 |
| CHEMBL4569923 | — | — | 1 | 4.89 |
| CHEMBL4439523 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4588827 | — | Ki | = | 7800.0 | nM | 5.11 |
| CHEMBL4569923 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL4439523 | — | Ki | = | 29000.0 | nM | 4.54 |