Assay Detail
Binding
CHEMBL4372467
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Partial agonist activity at human D1R
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel Strategies To Activate the Dopamine D<sub>1</sub> Receptor: Recent Advances in Orthosteric Agonism and Positive Allosteric Modulation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.51 | 8.07 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3697617 | TAVAPADON | 3.0 | 1 | 8.07 |
| CHEMBL3671276 | — | — | 1 | 6.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3697617 | TAVAPADON | Ki | = | 8.54 | nM | 8.07 |
| CHEMBL3671276 | — | Ki | = | 113.0 | nM | 6.95 |