Assay Detail
Binding
CHEMBL4373770
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse STING by isothermal titration calorimetric method
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Stimulator of interferon genes protein (CHEMBL4523311) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Interrupting cyclic dinucleotide-cGAS-STING axis with small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.46 | 5.46 |
| IC50 | 1 | 8.10 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4573298 | — | — | 1 | 8.10 |
| CHEMBL1569545 | CRIDANIMOD | 3.0 | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4573298 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL1569545 | CRIDANIMOD | Kd | = | 3500.0 | nM | 5.46 |