Assay Detail
ADMET
CHEMBL4374259
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Cytotoxicity against human HCT116 cells incubated for 48 hrs by Celltiter-blue assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
FgaPT2, a biocatalytic tool for alkyl-diversification of indole natural products.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.43 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL127277 | — | — | 1 | 4.96 |
| CHEMBL4437329 | — | — | 1 | 4.51 |
| CHEMBL4552566 | — | — | 1 | 4.46 |
| CHEMBL4451965 | — | — | 1 | 4.42 |
| CHEMBL4474524 | — | — | 1 | 4.24 |
| CHEMBL4448418 | — | — | 1 | 4.21 |
| CHEMBL4446906 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL127277 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4437329 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL4552566 | — | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL4451965 | — | IC50 | = | 38000.0 | nM | 4.42 |
| CHEMBL4474524 | — | IC50 | = | 58000.0 | nM | 4.24 |
| CHEMBL4448418 | — | IC50 | = | 62000.0 | nM | 4.21 |
| CHEMBL4446906 | — | IC50 | = | 61000.0 | nM | 4.21 |