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Assay Detail

CHEMBL4376319

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Human coronavirus 229E
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human coronavirus 229E
Confidence 1 — Organism
Curated By Autocuration

Target

Human coronavirus 229E (CHEMBL613837)
Type ORGANISM
Organism Human coronavirus 229E

Publication

Primaquine derivatives: Modifications of the terminal amino group.
Zorc B, Perković I, Pavić K, Rajić Z, Beus M.
Eur J Med Chem (2019) 182 : 111640 -111640
PubMed 31472472 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 5 5.10 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4165924 1 5.10
CHEMBL4163981 1 5.10
CHEMBL4162377 1 5.10
CHEMBL4176432 1 5.10
CHEMBL4165820 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4165924 EC50 = 7900.0 nM 5.10
CHEMBL4163981 EC50 = 7900.0 nM 5.10
CHEMBL4162377 EC50 = 7900.0 nM 5.10
CHEMBL4176432 EC50 = 7900.0 nM 5.10
CHEMBL4165820 EC50 = 7900.0 nM 5.10