Assay Detail
Functional
CHEMBL4376909
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Antiviral activity against recombinant RSV infected in HeLa cells assessed as reduction in eGFP expression after 3 days by laser microscopic analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 9.21 | 9.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4452455 | — | — | 1 | 9.60 |
| CHEMBL4437054 | RILEMATOVIR | 3.0 | 1 | 9.34 |
| CHEMBL4459588 | — | — | 1 | 8.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4452455 | — | EC50 | = | 0.25 | nM | 9.60 |
| CHEMBL4437054 | RILEMATOVIR | EC50 | = | 0.46 | nM | 9.34 |
| CHEMBL4459588 | — | EC50 | = | 2.0 | nM | 8.70 |