Compound Detail
CHEMBL4452455
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Basic Information
| ChEMBL ID | CHEMBL4452455 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WKDMORGVSPXDJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
457.4
MW (Da)
4.50
ALogP
6
HBA
0
HBD
57.6
PSA (Ų)
0.40
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Respiratory syncytial virus CHEMBL612679 | EC50 | 9.6 | 9.6 | 0.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus | EC50 | = | 0.25 | nM | 9.6 | Antiviral activity against recombinant RSV infected in HeLa cells assessed as re... | 30411898 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 30411898 | 10.1021/acs.jmedchem.8b01361 | Respiratory syncytial virus | 1 |
Data from ChEMBL 36 via Core Engine