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Assay Detail

CHEMBL4376924

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against RSV type B infected in Hep2 cells for 3 days by TMB-ELISA method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human respiratory syncytial virus
Confidence 1 — Organism
Curated By Autocuration

Target

Human orthopneumovirus (CHEMBL613127)
Type ORGANISM
Organism Human orthopneumovirus

Publication

State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
Cockerill GS, Good JAD, Mathews N.
J Med Chem (2019) 62 : 3206 -3227
PubMed 30411898 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 9.37 9.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3410450 PRESATOVIR 2.0 1 9.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3410450 PRESATOVIR EC50 = 0.43 nM 9.37