Assay Detail
Functional
CHEMBL4377281
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxic activity in human HCT116 cells assessed as reduction in cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Triphenylphosphonium Analogues of Betulin and Betulinic Acid with Biological Activity: A Comprehensive Review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.29 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4567231 | — | — | 1 | 5.46 |
| CHEMBL4437510 | — | — | 1 | 5.40 |
| CHEMBL312687 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4567231 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL4437510 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL312687 | — | IC50 | = | 9600.0 | nM | 5.02 |