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Assay Detail

CHEMBL4378075

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antimalarial activity against Plasmodium vivax assessed as reduction in parasite growth after 72 hrs by SYBR-green based fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium vivax
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium vivax (CHEMBL613013)
Type ORGANISM
Organism Plasmodium vivax

Publication

The Development Process for Discovery and Clinical Advancement of Modern Antimalarials.
Ashton TD, Devine SM, Möhrle JJ, Laleu B, Burrows JN, Charman SA, Creek DJ, Sleebs BE.
J Med Chem (2019) 62 : 10526 -10562
PubMed 31385706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.26 8.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2058833 GANAPLACIDE 2.0 1 8.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2058833 GANAPLACIDE EC50 = 5.5 nM 8.26