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Target Snapshot

CHEMBL613013 Target Snapshot

Plasmodium vivax · ORGANISM · Plasmodium vivax

Back to Search Search this target Browse approvals Evidence Card
45Compounds
60Assays
9Approved Drugs
142.0Activities
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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Confirm a stable target identifier before relying on this context across project surfaces.

Review focus
Open DB context pending

Confirm a stable target identifier before relying on this context across project surfaces.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Plasmodium vivax as ChEMBL target CHEMBL613013. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Plasmodium vivax
ORGANISM · Plasmodium vivax
As of 2026-09-13
ChEMBL target ID
CHEMBL613013
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Plasmodium vivax still has a stable protein naming contract across sources.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

Preferred NamePlasmodium vivax
Target TypeORGANISM
OrganismPlasmodium vivax
ChEMBL ↗ NCBI Taxonomy ↗

Next Actions

SearchRun a focused querySearch the database using this target name as the starting context. ApprovalsCheck approved moleculesSee which approved drugs connect back to this target and its surrounding signal space. FeedScan papers & updatesStay in the project thread while checking recent papers and platform updates.
UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelPlasmodium vivax
UniProt AccessionN/A

Plasmodium vivax

Source · UniProt accession via ChEMBL component mapping
UniProt Context ↗
Review Cue

How to read this target

Review this target as Plasmodium vivax.

Review namePlasmodium vivax
OrganismPlasmodium vivax
Clinical Profile

Clinical Phase Distribution

9
Approved
2
Phase III
4
Phase II
Assay Mix

Activity Type Distribution

IC50115.0
EC5027.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL361497 9.41 IC50 0.39 Approved
CHEMBL5177195 9.3 EC50 0.5 Preclinical
CHEMBL405110 8.92 IC50 1.2 Approved
CHEMBL1800836 8.85 IC50 1.4 Preclinical
CHEMBL5173264 8.7 EC50 2.0 Clinical
CHEMBL35228 8.62 IC50 2.4 Clinical
CHEMBL5183385 8.52 IC50 3.0 Preclinical
CHEMBL5421033 8.39 EC50 4.07 Preclinical
CHEMBL5417822 8.35 IC50 4.5 Preclinical
CHEMBL405862 8.29 EC50 5.129 Preclinical
Distribution

pChEMBL Value Distribution

1
5.0
6
5.5
13
6.0
11
6.5
20
7.0
41
7.5
22
8.0
14
8.5
6
9.0
0
9.5
pChEMBL
Approved Drugs

Approved Drugs

ARTESUNATE
CHEMBL361497
Approved 2020
Properties Compare Identifier
METHYLENE BLUE ANHYDROUS
CHEMBL405110
Approved 2011
Properties Compare Identifier
LUMEFANTRINE
CHEMBL38827
Approved 2009
Properties Compare Identifier
VORINOSTAT
CHEMBL98
Approved 2006
Properties Compare Identifier
MEFLOQUINE
CHEMBL416956
Approved 1989
Properties Compare Identifier
CHLOROQUINE
CHEMBL76
Approved 1949
Properties Compare Identifier
Assay Landscape

Assay Landscape

66
Total Assays
29
Tested Compounds
1
Assay Types
Functional — 66 assays, 29 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 65 29 7.6
assay format 1 0 —

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine