Assay Detail
ADMET
CHEMBL4379883
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Cytotoxicty activity against human WI38 cells measured after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.47 | 4.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4587101 | — | — | 1 | 4.63 |
| CHEMBL4550437 | — | — | 1 | 4.44 |
| CHEMBL3976024 | — | — | 1 | 4.40 |
| CHEMBL4521083 | — | — | 1 | 4.39 |
| CHEMBL4571323 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4587101 | — | IC50 | = | 23500.0 | nM | 4.63 |
| CHEMBL4550437 | — | IC50 | = | 36600.0 | nM | 4.44 |
| CHEMBL3976024 | — | IC50 | = | 39900.0 | nM | 4.40 |
| CHEMBL4521083 | — | IC50 | = | 40890.0 | nM | 4.39 |
| CHEMBL4571323 | — | IC50 | = | 124600.0 | nM | - |