Assay Detail
Binding
CHEMBL4380584
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to porcine brain tubulin polymerization by surface plasmon analysis analysis
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Structure-Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.27 | 5.58 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4468642 | — | — | 2 | 5.58 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 4.95 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4468642 | — | Kd | = | 2660.0 | nM | 5.58 |
| CHEMBL107 | COLCHICINE | Kd | = | 11300.0 | nM | 4.95 |
| CHEMBL4468642 | — | Activity | - | — | - |