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Assay Detail

CHEMBL4382893

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK cell membranes after 1 hr by liquid scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Melanocortin receptor 4 (CHEMBL259)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New Modalities, Technologies, and Partnerships in Probe and Lead Generation: Enabling a Mode-of-Action Centric Paradigm.
Valeur E, Jimonet P.
J Med Chem (2018) 61 : 9004 -9029
PubMed 29851477 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.54 7.54

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4211294 1 7.54

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4211294 Ki = 29.0 nM 7.54