Assay Detail
Binding
CHEMBL4383288
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of full-length 6His-tagged Mycobacterium tuberculosis H37Rv Ddl expressed in Escherichia coli BL21(DE3)pLysS by UV-Vis spectrophotometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis H37Rv |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.60 | 4.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL771 | CYCLOSERINE | 4.0 | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL771 | CYCLOSERINE | Ki | = | 25000.0 | nM | 4.60 |