Assay Detail
Binding
CHEMBL4383864
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human factor 9a preincubated for 30 mins followed by substrate addition and measured for 20 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of anthranilamide derivatives as potential factor Xa (fXa) inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.47 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4469752 | — | — | 1 | 7.58 |
| CHEMBL4441346 | — | — | 1 | 7.44 |
| CHEMBL4469308 | — | — | 1 | 7.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4469752 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL4441346 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL4469308 | — | IC50 | = | 42.0 | nM | 7.38 |