Assay Detail
ADMET
CHEMBL4385022
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | WI-38 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Melanogenesis-Inhibitory and Cytotoxic Activities of Triterpene Glycoside Constituents from the Bark of Albizia procera.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.39 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4451985 | — | — | 1 | 5.66 |
| CHEMBL4561300 | — | — | 1 | 5.60 |
| CHEMBL4581280 | — | — | 1 | 5.32 |
| CHEMBL4483588 | — | — | 1 | 5.29 |
| CHEMBL4448517 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4451985 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL4561300 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL4581280 | — | IC50 | = | 4800.0 | nM | 5.32 |
| CHEMBL4483588 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL4448517 | — | IC50 | = | 8300.0 | nM | 5.08 |