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Assay Detail

CHEMBL4385753

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AChE (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease.
Wang T, Liu XH, Guan J, Ge S, Wu MB, Lin JP, Yang LR.
Eur J Med Chem (2019) 169 : 200 -223
PubMed 30884327 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL11805 CAPROCTAMINE 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL11805 CAPROCTAMINE IC50 = 169.82 nM 6.77