Assay Detail
Binding
CHEMBL4386402
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Inhibition of tubulin polymerization (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Anti-tubulin agents of natural origin: Targeting taxol, vinca, and colchicine binding domains.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.72 | 8.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4575066 | — | — | 1 | 8.85 |
| CHEMBL2024544 | — | — | 1 | 8.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4575066 | — | IC50 | = | 1.4 | nM | 8.85 |
| CHEMBL2024544 | — | IC50 | = | 2.6 | nM | 8.59 |