Assay Detail
ADMET
CHEMBL4388917
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP2C19 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of a novel series of cyanoindole derivatives as potent γ-secretase modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.87 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4451760 | — | — | 1 | 5.08 |
| CHEMBL4466805 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4451760 | — | IC50 | = | 8300.0 | nM | 5.08 |
| CHEMBL4466805 | — | IC50 | = | 22100.0 | nM | 4.66 |